The Future of Quitting: A Nicotine Vaccine - ACS Headline Science


How does the new vaccine against nicotine addiction



The vaccine was developed at Weill Cornell Medical College, where experimental animals successfully demonstrated the ability of the liver to produce antibodies that neutralize the action of nicotine using a new drug. Scientists have long been working in this direction, ensuring that the body itself cleans the blood from the poison.
Under the action of the vaccine, the body creates its own antibodies and develops immunity to nicotine addiction. Preparations that were tested earlier required repeated, repeated, costly injections. It was difficult to calculate the dose of funds, since their action was strictly individual.
The new vaccine will be a salvation for smokers who have already experienced all existing options for the fight, but were defeated. According to statistics, about 80% of people who quit smoking, again returned to their habit.
Scientists are constantly looking for new ways to make the body give up nicotine addiction. Before the new drug, there were two types of vaccines: active and passive. The first type is a foreign agent for human immunity, the body sees the "scout" and produces antibodies against it. But the tiny nicotine molecule was not integrated into the active vaccine. The second type is a passive vaccine from the whole complex of ready-made antibodies, which are necessary for the development of immunity.
The research department of the Vale Cornell has developed a third species - the genetic vaccine. Scientists have designed antibodies that neutralize nicotine, and put them into a virus that does not adversely affect humans. After interacting with a genetic vaccine, liver cells begin to produce their antibodies, and in large quantities.
Most importantly, only a very small part of the poisonous nicotine reaches the smoker's brain. As a result, a person will not get what he expects from a cigarette, and without this pleasure, the very meaning of this harmful habit is lost. The vaccine can also be used as a prophylactic agent in order to eliminate the occurrence of nicotine addiction.
The vaccine has not yet been tested in humans, and rats and primates are next in line, but the mice that participated in the experiment feel no worse than before it began.



Video: HEALTH: A vaccine against...nicotine!

Nicotine Vaccine, Mouth Spray Are New Tools To Stop Smoking
How does the new vaccine against nicotine addiction





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